Journal: Npj Biosensing

Article Title: Plasmonic biosensors and actuators for integrated point-of-care diagnostics

doi: 10.1038/s44328-025-00050-1

Figure Lengend Snippet: a Biacore SPR sensor chip provides real-time, ready-to-go analysis of a wide range of molecular interactions, providing kinetics, affinity, and binding data (Credit: Cytiva Life Sciences (cytivalifesciences.com)). b Carterra SPR sensors integrate with HT-SPR technology, enabling fragments and small molecules screening and antibody discovery. c Detection principle of NG-Test CARBA 5 Lateral Flow Assay, NG Biotech. Reprinted with permission from ref. . Copyright 2018 Oxford Academic. d Principle of detection method for Nucleic Acid Lateral Flow Immunoassay (NALFIA), Pocket Diagnostic. Reprinted with permission from ref. . Copyright 2024 Springer Nature. e Klarite SERS substrate on an array of inverted pyramid structures (credit: optics.org). Reprinted with permission from ref. . Copyright 2011 Applied Spectroscopy. f Commercial Ocean Insight SERS substrate made of gold or silver, mounted in a microscope slide. Reprinted with permission from ref. . Copyright 2023 Springer Nature. g Nanopartz Plasmonic PCR and its 8-channels for POC system (credit: Nanopartz Inc. (nanopartz.com)). h Nexless P – IV transforms is an innovative Plasmonic PCR Technology, combining advanced plasmonic gold nanorod nanoparticles with real-time quantitative PCR. (Credit: Nexless Healthcare (nexlesshealthcare.ca)).

Article Snippet: Biacore SPR biosensors are designed with three core technologies: an optical detector system, a 50-nm layer of gold on the sensor chip, a microfluidic chip and liquid handling system .

Techniques: Binding Assay, Lateral Flow Assay, Diagnostic Assay, Spectroscopy, Microscopy, Real-time Polymerase Chain Reaction